About this Course
4.6
13 ratings
3 reviews
Specialization

Course 7 of 7 in the

100% online

100% online

Start instantly and learn at your own schedule.
Flexible deadlines

Flexible deadlines

Reset deadlines in accordance to your schedule.
Beginner Level

Beginner Level

Hours to complete

Approx. 17 hours to complete

Suggested: 3 weeks of study, 3-4 hours/week...
Available languages

English

Subtitles: English...
Specialization

Course 7 of 7 in the

100% online

100% online

Start instantly and learn at your own schedule.
Flexible deadlines

Flexible deadlines

Reset deadlines in accordance to your schedule.
Beginner Level

Beginner Level

Hours to complete

Approx. 17 hours to complete

Suggested: 3 weeks of study, 3-4 hours/week...
Available languages

English

Subtitles: English...

Syllabus - What you will learn from this course

Week
1
Hours to complete
5 hours to complete

Week 1: Identifying the Culprit in a Food Poisoning Outbreak

This week, we will apply genome sequencing algorithms to identify the bacterium causing a deadly food poisoning outbreak....
Reading
4 readings, 1 quiz
Reading4 readings
Welcome to Class!10m
Special Thanks2m
Introduction15m
Databases and Tools5m
Week
2
Hours to complete
4 hours to complete

Week 2: Comparing Gene Expression in Tissue Samples with RNA-Seq

In this week's Application Challenge, we will learn how RNA-Sequencing can be applied to perform tissue-level gene expression analysis. In particular, which is more similar on a gene expression level: different tissues from the same organism, or analogous tissues from related species? This question was the subject of recent debate and a Twitter controversy -- read more to find out!...
Reading
2 readings, 1 quiz
Reading2 readings
Introduction15m
Databases and Tools5m
Week
3
Hours to complete
5 hours to complete

Week 3: Weighing the Pros and Cons of Whole Genome and Whole Exome Sequencing on a Human Sample

Comparing the differences between sequencing an entire human genome and sequencing only the exome, or the DNA that is eventually translated into protein. Can we obtain a complete picture of someone's genetic disease predispositions from only the exome, or is there information lurking in introns that can provide doctors with vital information? How do we weigh the trade-offs when considering genome and exome sequencing?...
Reading
4 readings, 1 quiz
Reading4 readings
Introduction15m
Databases and Tools10m
Walkthroughs15m
Reading: Part 3 FAQsm

Instructors

Avatar

Phillip Compeau

Visiting Researcher
Department of Computer Science & Engineering
Avatar

Pavel Pevzner

Professor
Department of Computer Science and Engineering

About University of California San Diego

UC San Diego is an academic powerhouse and economic engine, recognized as one of the top 10 public universities by U.S. News and World Report. Innovation is central to who we are and what we do. Here, students learn that knowledge isn't just acquired in the classroom—life is their laboratory....

About the Bioinformatics Specialization

Join Us in a Top 50 MOOC of All Time! How do we sequence and compare genomes? How do we identify the genetic basis for disease? How do we construct an evolutionary Tree of Life for all species on Earth? When you complete this Specialization, you will learn how to answer many questions in modern biology that have become inseparable from the computational approaches used to solve them. You will also obtain a toolkit of existing software resources built on these computational approaches and that are used by thousands of biologists every day in one of the fastest growing fields in science. Although this Specialization centers on computational topics, you do not need to know how to program in order to complete it. If you are interested in programming, we feature an "Honors Track" (called "hacker track" in previous runs of the course). The Honors Track allows you to implement the bioinformatics algorithms that you will encounter along the way in dozens of automatically graded coding challenges. By completing the Honors Track, you will be a bioinformatics software professional! Learn more about the Bioinformatics Specialization (including why we are wearing these crazy outfits) by watching our introductory video. You can purchase the Specialization's print companion, Bioinformatics Algorithms: An Active Learning Approach, from the textbook website. Our first course, "Finding Hidden Messages in DNA", was named a top-50 MOOC of all time by Class Central!...
Bioinformatics

Frequently Asked Questions

  • Once you enroll for a Certificate, you’ll have access to all videos, quizzes, and programming assignments (if applicable). Peer review assignments can only be submitted and reviewed once your session has begun. If you choose to explore the course without purchasing, you may not be able to access certain assignments.

  • When you enroll in the course, you get access to all of the courses in the Specialization, and you earn a certificate when you complete the work. Your electronic Certificate will be added to your Accomplishments page - from there, you can print your Certificate or add it to your LinkedIn profile. If you only want to read and view the course content, you can audit the course for free.

More questions? Visit the Learner Help Center.