About this Course
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Approx. 11 hours to complete

English

Subtitles: English

Skills you will gain

Clinical ResearchTrial DesignClinical Trial DesignClinical Trial Management

100% online

Start instantly and learn at your own schedule.

Flexible deadlines

Reset deadlines in accordance to your schedule.

Approx. 11 hours to complete

English

Subtitles: English

Syllabus - What you will learn from this course

Week
1
2 hours to complete

Types of Trial Designs

This week, we explore different types of trial designs, including parallel, crossover, group allocation, factorial, large simple, equivalency, non-inferiority, and adaptive designs....
5 videos (Total 56 min), 3 readings, 1 quiz
5 videos
Lecture 1A: Comparison Structure: Parallel, Crossover, and Group Allocation Designs18m
Lecture 1B: Extensions of the Parallel Design: Factorial and Large Simple Designs10m
Lecture 1C: Testing for Hypotheses Other than Superiority: Equivalency and Non-Inferiority Designs12m
Lecture 1D: Adaptive Design11m
3 readings
Welcome Message10m
Syllabus10m
Pre-Course Survey10m
1 practice exercise
Quiz 120m
Week
2
2 hours to complete

Randomization and Masking

This week we discuss two key design features of randomized clinical trials used to protect against bias, randomization and masking....
3 videos (Total 67 min), 1 reading, 1 quiz
3 videos
Lecture 2B: Types of Schemes32m
Lecture 3: Masking18m
1 reading
Welcome to Week 210m
1 practice exercise
Quiz 220m
Week
3
2 hours to complete

Outcomes and Analysis

This week focuses on a key design issue - selecting the primary outcome. We will also cover the gold standard for analysis of clinical trials, which is including all the participants in the analysis regardless of their actual treatment....
4 videos (Total 51 min), 1 reading, 1 quiz
4 videos
Lecture 4B: Influence on Design12m
Lecture 5A: Analysis by Assigned Treatment (Intention to Treat)10m
Lecture 5B: Subgroup Analysis6m
1 reading
Welcome to Week 310m
1 practice exercise
Quiz 320m
Week
4
2 hours to complete

Ethics

This week focuses on a key issue in the field of clinical trials, the ethics of experimentation in humans. ...
2 videos (Total 17 min), 6 readings, 1 quiz
2 videos
Lecture 6B: Contemporary Ethical Issues5m
6 readings
Welcome to Week 410m
The Belmont Report10m
Common Rule 45CFR4610m
Declaration of Helsinki10m
HIPAA Privacy Rule Booklet10m
The Nuremberg Code10m
1 practice exercise
Quiz 420m
4.7
233 ReviewsChevron Right

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started a new career after completing these courses

36%

got a tangible career benefit from this course

10%

got a pay increase or promotion

Top Reviews

By TSJul 4th 2018

High quality course ! covering important areas and detailed lectures, more and better than a mere introduction. Congrats ! My only regret : I'd have liked to hear more about NI and equivalence trials

By TJJun 2nd 2018

The instructors have broken down the concepts in a very effective manner and have designed very thoughtful discussion prompts. The course really helped me understand the basics of clinical trials.

Instructors

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Janet Holbrook, PhD, MPH

Associate Professor, Epidemiology
Bloomberg School of Public Health
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Lea T. Drye, PhD

Assistant Scientist, Epidemiology
Bloomberg School of Public Health

About Johns Hopkins University

The mission of The Johns Hopkins University is to educate its students and cultivate their capacity for life-long learning, to foster independent and original research, and to bring the benefits of discovery to the world....

Frequently Asked Questions

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