About this Course
4.6
35 ratings
8 reviews
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Start instantly and learn at your own schedule.
Flexible deadlines

Flexible deadlines

Reset deadlines in accordance to your schedule.
Intermediate Level

Intermediate Level

Hours to complete

Approx. 7 hours to complete

Suggested: 7 weeks of study, 1-3 hours/week...
Available languages

English

Subtitles: English...
100% online

100% online

Start instantly and learn at your own schedule.
Flexible deadlines

Flexible deadlines

Reset deadlines in accordance to your schedule.
Intermediate Level

Intermediate Level

Hours to complete

Approx. 7 hours to complete

Suggested: 7 weeks of study, 1-3 hours/week...
Available languages

English

Subtitles: English...

Syllabus - What you will learn from this course

Week
1
Hours to complete
1 hour to complete

Week 1

A brief history of extracellular measurements, and an example of such a recording. The goal is to understand the amplitudes and time variation of such measurements, as well as learn about some interesting and useful historical events....
Reading
3 videos (Total 20 min), 3 readings, 1 quiz
Video3 videos
The First Extracellular Measurements5m
Observing Wave Forms Between Human Hands7m
Reading3 readings
Course Overview10m
Assessments, Grading and Certificates10m
Week 1 Slides10m
Quiz1 practice exercise
120m
Week
2
Hours to complete
2 hours to complete

Week 2

A presentation of the cylindrical fiber model of a nerve. The goal is to see how this geometrically simple model of a nerve actually is sufficient to explain complex bioelectric events within and around electrically active tissue. One learns that currents are driven forward by voltages across cell membranes,. Current loops are created, with some parts of the current loop inside and other parts outside the active cells. Electrical potentials are created by the current loops, and are positive when these are approaching, negative when they are receding. In so doing they form the basis of all extracellular wave forms....
Reading
9 videos (Total 44 min), 3 readings, 1 quiz
Video9 videos
Left or right side stimulation5m
Simultaneous stimulation model2m
Definitions and questions6m
Origin in the membrane6m
Big loops as well as small4m
Approaching wave forms5m
Departing wave forms3m
Observations4m
Reading3 readings
Cylinderical Fiber Model Slides9m
Current Loops Slides10m
Current Loops and the Extracellular Waveforms Slides10m
Quiz1 practice exercise
224m
Week
3
Hours to complete
1 hour to complete

Week 3

Notable and useful aspects of extracellular wave forms are their changes in shape. What causes such changes? Two illuminating examples are studied, one that does not, and then another that does....
Reading
7 videos (Total 33 min), 3 readings, 1 quiz
Video7 videos
Vm and current inside3m
Vm patterns3m
Current loops3m
Experimental setup, cardiac Purkinje6m
Stimulation at the left or right3m
Stimulation at both ends, collision5m
Reading3 readings
When do Wave Shapes Change? Slides10m
Simultaneous Left and Right Stimulation Slides10m
Experimental Data Slides10m
Quiz1 practice exercise
324m
Week
4
Hours to complete
1 hour to complete

Week 4

Weeks 1 to 3 present some intriguing concepts and explain them with drawings and sketches. Do the wave forms so drawn have any connection with real tissue? Indeed they do. The goal of this week is to examine some specific experimental wave forms that were measured in cardiac Punkinje fibers, and to compare them those anticipated in earlier weeks.Week 4 is the end of the standard course. The remaining weeks are for honors study....
Reading
4 videos (Total 17 min), 1 reading, 1 quiz
Video4 videos
Two-fiber model, asynchronous2m
Experimental findings6m
Multiphasic summary3m
Reading1 reading
Multiphasic Recordings Slides10m
Quiz1 practice exercise
424m
4.6
8 ReviewsChevron Right

Top Reviews

By AJApr 15th 2018

Great follow up course to the previous within the installment regarding bioelectricity. Taught me quite a lot and am looking forward to further releases to the series if they are in the works.

By PWMar 8th 2017

Having been out school for over 30 years this was a very challenging but rewarding course for myself. I'm glad i took it

Instructor

Avatar

Dr. Roger Barr

Anderson-Rupp Professor of Biomedical Engineering and Associate Professor of Pediatrics
Biomedical Engineering, Pediatrics

About Duke University

Duke University has about 13,000 undergraduate and graduate students and a world-class faculty helping to expand the frontiers of knowledge. The university has a strong commitment to applying knowledge in service to society, both near its North Carolina campus and around the world....

Frequently Asked Questions

  • Once you enroll for a Certificate, you’ll have access to all videos, quizzes, and programming assignments (if applicable). Peer review assignments can only be submitted and reviewed once your session has begun. If you choose to explore the course without purchasing, you may not be able to access certain assignments.

  • When you purchase a Certificate you get access to all course materials, including graded assignments. Upon completing the course, your electronic Certificate will be added to your Accomplishments page - from there, you can print your Certificate or add it to your LinkedIn profile. If you only want to read and view the course content, you can audit the course for free.

  • No. Completion of a Coursera course does not earn you academic credit from Duke; therefore, Duke is not able to provide you with a university transcript. However, your electronic Certificate will be added to your Accomplishments page - from there, you can print your Certificate or add it to your LinkedIn profile.

More questions? Visit the Learner Help Center.