About this Course
4.7
147 ratings
48 reviews
100% online

100% online

Start instantly and learn at your own schedule.
Flexible deadlines

Flexible deadlines

Reset deadlines in accordance to your schedule.
Hours to complete

Approx. 31 hours to complete

Suggested: 视频,补充材料和测验共20小时...
Available languages

Chinese (Simplified)

Subtitles: Chinese (Simplified)
100% online

100% online

Start instantly and learn at your own schedule.
Flexible deadlines

Flexible deadlines

Reset deadlines in accordance to your schedule.
Hours to complete

Approx. 31 hours to complete

Suggested: 视频,补充材料和测验共20小时...
Available languages

Chinese (Simplified)

Subtitles: Chinese (Simplified)

Syllabus - What you will learn from this course

Week
1
Hours to complete
2 hours to complete

导论与历史

欢迎选学“生物信息学:导论与方法”网上课程!完成本模块的课程后你将可以:熟悉生物信息学的基本概念;了解生物信息这一年轻领域的历史;体会生物信息学的迅猛发展。课程补充材料可以加深你对课程讲座内容的理解,虽然小测和考试对这些内容不作要求。...
Reading
4 videos (Total 67 min), 2 readings, 1 quiz
Video4 videos
什么是生物信息学 16m
生物信息学历史34m
中国大陆的生物信息学7m
Reading2 readings
阅读参考10m
讲义10m
Quiz1 practice exercise
导论与历史20m
Week
2
Hours to complete
3 hours to complete

序列比对

完成本模块的课程后你将可以: 掌握基于动态规划编程思想的序列比对算法; 区分Needleman-Wunsch全局比对算法和Smith-Waterman局部比对算法; 了解空位罚分背后的原理和计算算法的复杂度将帮助你在你自己的研究中应用现有的生物信息学工具; 你还可以一睹Smith-Waterman算法的发明人Michael Waterman博士的风采。...
Reading
8 videos (Total 114 min), 2 readings, 1 quiz
Video8 videos
利用动态规划进行全局比对15m
从全局比对到局部比对6m
考虑仿射空位罚分的序列比对,以及如何计算Needleman-Wunsch算法的时间复杂度6m
关于同源、相似性、相似性矩阵和点阵图10m
M.S. Waterman教授访谈 29m
学生课堂报告(一)18m
学生课堂报告(二)11m
Reading2 readings
阅读参考10m
讲义10m
Quiz1 practice exercise
序列比对18m
Week
3
Hours to complete
1 hour to complete

序列数据库搜索

完成本模块的课程后你将可以:熟悉序列数据库搜索和最常见的序列数据库;领略BLAST背后算法的奥妙;掌握日后在你自己的科研项目中调节BLAST参数的方法。...
Reading
3 videos (Total 37 min), 2 readings, 1 quiz
Video3 videos
BLAST算法初探10m
学生课堂报告15m
Reading2 readings
阅读参考10m
讲义10m
Quiz1 practice exercise
序列数据库搜索10m
Week
4
Hours to complete
2 hours to complete

马尔可夫模型

完成本模块的课程后你将可以:了解状态转移、马尔科夫链、马尔科夫模型的基本概念;亲手完成一个隐马尔科夫模型;利用隐马尔可夫模型在一个实际的生物学问题中作出预测。...
Reading
7 videos (Total 70 min), 2 readings, 1 quiz
Video7 videos
隐马尔可夫模型 9m
用隐马尔可夫模型建立预测模型 8m
学生课堂报告(一)16m
学生课堂报告(二)11m
学生课堂报告(三)8m
学生实践8m
Reading2 readings
阅读参考10m
讲义10m
Quiz1 practice exercise
马尔可夫模型14m

Instructors

Avatar

Ge Gao 高歌, Ph.D.

Assistant Professor, Principle Investigator
Center for Bioinformatics, School of Life Science
Avatar

Liping Wei 魏丽萍, Ph.D.

Professor, Director
Center for Bioinformatics, School of Life Sciences

About Peking University

Peking University is determined to make its education openly accessible to students in China and around the world. With over 3000 faculty members, Peking University offers excellence in teaching and learning. Founded in 1898, Peking University (PKU) was the first national comprehensive university in China. For the past 115 years, with its hundreds of thousands of outstanding alumni, Peking University has made prominent contributions in the humanities and sciences to further China's prosperity and progress....

Frequently Asked Questions

  • Once you enroll for a Certificate, you’ll have access to all videos, quizzes, and programming assignments (if applicable). Peer review assignments can only be submitted and reviewed once your session has begun. If you choose to explore the course without purchasing, you may not be able to access certain assignments.

  • When you purchase a Certificate you get access to all course materials, including graded assignments. Upon completing the course, your electronic Certificate will be added to your Accomplishments page - from there, you can print your Certificate or add it to your LinkedIn profile. If you only want to read and view the course content, you can audit the course for free.

More questions? Visit the Learner Help Center.