All right, so the next disease or condition
we'll talk about is hyperkalemic periodic paralysis, or HYPP.
Now, this one isn't lethal, so, so of all
the genetic diseases we'll cover, this is the, the
nicer of them, which, none of them are nice,
but this one is, is in particular not too bad.
And it's, it's really causing a muscle disease so what happens is, is in, in
our muscles or in any mammalian, mammalian
system, you have these sodium ion channels, okay.
And so they control.
The amount of sodium that can get in to a cell, and when
we get sodium in, in a muscle cell that actually fires or contracts.
Well, in this disease those, those ion channels are disrupted.
They don't function properly, so you actually
get leakage of sodium into the muscles.
And then, this is where those muscles involuntary contract or they twitch.
So that, that's how we see this in, in, in these animals that have it.
You know they, they, they twitch quite a
lot or really have a lot of muscle weakness.
So this was again an inbreeding situation where we were trying.
You know, earlier in the quarter horse industry, they were, they
were really trying to develop these, these really muscular, you know.
Strong-looking animals, and it develop, unfortunately, it developed this disease.
So they, they actually traced this disease to a sire called Impressive,
and he's what is called, he's known an Appendix quarter horse, or
a quarter horse with, with quite a bit of thorough bred blood
lines in them or thorough bred breeding, so those are known as [INAUDIBLE].
And you can obviously see this in paints and some
appaloosa horses, that you know, where you get some of that
quarter horse influence in there, so that's where it originated and